Omics · study · 2026
PAR1 signaling in hematopoietic stem and progenitor cells
Listed in NCBI GEO
Here, we investigated the effects of activated Protein C (aPC) and thrombin (THR) on human CD34+ hematopoieitc stem and progenitor cells (HSPC) enriched from mobilized peripheral blood of 1 healthy donor.
Description
Both aPC and THR act on protease-activated receptors. In this data set, CD34+ were stimulated for two different timepoints: 4h to measure intermendiate changes of gene expression and 24h to investigate potential long-term changes in gene expression and differentiation.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE313nnn/GSE313745 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE313745 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1381526 ncbi.nlm.nih.gov/bioproject/PRJNA1381526 ↗
project · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Homo sapiens
- From keywords
- Life Sciences
Provenance · 1 source records, 7 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE313745 | 15 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |