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Excel · study · 2026

RNA-seq analysis of CSNK2B and P300 knockdown in NCI-H69 small cell lung cancer cells

Listed in NCBI GEO

This submission contains bulk RNA-seq data from NCI-H69 small cell lung cancer cells transfected with negative control siRNA, CSNK2B-targeting siRNA, or P300-targeting siRNA.

Description

Total RNA was collected 48 hours after transfection. The dataset was generated to investigate transcriptional programs regulated by the CSNK2B/RBBP4/P300 complex in small cell lung cancer, particularly genes and pathways related to DNA damage repair and NF-kappa B signaling.

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Stated by source
Expression profiling by high throughput sequencing · Homo sapiens
From keywords
Life Sciences
Inferred from text
Cancer 75% · RNA sequencing 65%
Provenance · 1 source records, 9 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE33750315 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[disease].local:disease:cancerenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (75%)
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[modality].local:modality:rna-seqenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (65%)
concepts[organism].NCBITaxon:9606source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title