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Omics · study · 2026

Single-nucleus multiome (snRNA-seq + snATAC-seq) of E14.5 mouse skin dermis in Shh cKO condition

Listed in NCBI GEO

Mouse embryonic skin samples were collected at E14.5.

Description

Dorsolateral skin from littermate control and K14Cre;Shh^fl/fl (Shh cKO) mutant embryos was dissected and processed for 10x Genomics Multiome (simultaneous snRNA-seq and snATAC-seq). Nuclei were isolated and subjected to the Chromium Single Cell Multiome ATAC + Gene Expression protocol.

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Life Sciences
Inferred from text
Genetics 71% · Single-cell RNA sequencing 65%
Provenance · 1 source records, 10 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE34228115 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].anzsrc:group:3105enrichment · NCBI GEOtaxonomy-embedding@1.1.0title+keywords+description (71%)
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[method].geo_series_type:genome-binding-occupancy-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[modality].local:modality:single-cell-rna-seqenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (65%)
concepts[organism].NCBITaxon:10090source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title