Supplementary file 1_Association between intrinsic capacity and trajectories of physical function among older adults: findings from a 10-year longitudinal cohort study.docx

Objectives<p>To identify trajectories of basic activities of daily living (BADL) and instrumental activities of daily living (IADL) and determine whether the baseline intrinsic capacity (IC) deficit score predicts 10-year functional decline in older adults.</p>Methods<p>Data were from the Chinese Longitudinal Healthy Longevity Survey (2008–2018, N = 2,045). A six-domain IC deficit score was constructed using the Integrated Care for Older People (ICOPE) framework.

Group-based trajectory modeling, generalized linear models, and multilevel mixed-effects models (stratified by age) were used.</p>Results<p>Two BADL trajectories (high-stable 81.9%; high-declining 18.1%) and three IADL trajectories (mild, moderate, severe decline) were identified. A higher IC deficit score predicted declining BADL (odds ratio [OR] = 1.22, 95% confidence interval [CI]: 1.09–1.37), severe IADL decline (OR = 1.94, 95%CI: 1.66–2.27), and moderate IADL decline (OR = 1.37, 95%CI: 1.22–1.53).