Data Sheet 1_The resveratrol monomer enhances resistance to bacterial pathogen through the activation of SA-NPR1 signaling pathway in Arabidopsis.docx

Although its direct antimicrobial effects have been investigated extensively, its role and regulatory mechanism in plant immune signaling remain unclear. In this study, we demonstrate that resveratrol enhances resistance to bacterial pathogens through activation of endogenous defense pathways in Arabidopsis thaliana.

Resveratrol treatment reduced disease symptoms and bacterial growth caused by Pseudomonas syringae pv. tomato DC3000 (Pst DC3000) without exerting direct antibacterial activity and increased transcription of PATHOGENESIS-RELATED (PR) genes. Resveratrol promoted translocation of NONEXPRESSOR OF PATHOGENESIS-RELATED GENES 1 (NPR1) into the nuclear and failed to confer resistance in the npr1–1 mutant, which demonstrates that NPR1-mediated signaling is required for this response.