Omics · study · 2026
scRNAseq of brain micrometastasis
Listed in NCBI GEO
Heterogeneity of brain micrometastasis was analyzed by terms of intracardiac injection of H2030-BrM cell (lung adenocarcinoma model with tropism to the brain) into mice.
Description
After 14 days, mice were sacrified in order to obtain metastatic cells from micrometastases performing vascular co-option and in proliferative pause to study their heterogeneity. Apart from control cells, H2030-BrM with reduced levels of MXD4 (shRNAs), a discovered driver of the prolfierative pause, were also injected and analyzed by scRNAseq to compare their differences.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE278nnn/GSE278126 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE278126 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1165746 ncbi.nlm.nih.gov/bioproject/PRJNA1165746 ↗
project · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Homo sapiens
- From keywords
- Life Sciences
Provenance · 1 source records, 7 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE278126 | 12 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |