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Archive · study · 2026

Spatial transcriptomic comparison between IPF and donor lung distal explant tissue

Listed in NCBI GEO

Pulmonary fibrosis remains a significant public health concern due to an increasing incidence and limited treatment options.

Description

Alveolar type 2 epithelial cell (AT2) senescence causes stem cell exhaustion and progenitor failure, leading to ineffective and aberrant alveolar repairs and unresolved fibrosis. AT2 senescence regulatory molecules require additional studies.

The spatial transcriptomics study we present here is aiming to comparing end stage IPF explant tissue with donor distal tissue to better understand the molecular changes associated with diseases.

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Stated by source
Homo sapiens · Other
From keywords
Life Sciences
Provenance · 1 source records, 7 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE29295615 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:othersource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[organism].NCBITaxon:9606source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title