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Omics · study · 2026

Gene expression profiling by RNA-Seq analysis of mice carrying an inner-ear conditional knockout of Esrrg.

Listed in NCBI GEO

Estrogen-related receptor gamma (ESRRG), an orphan nuclear receptor with structural homology to the classical estrogen receptors, is widely recognised as a key metabolic regulator.

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Clinical studies have suggested a link between ESRRG and auditory function; however, the biological mechanisms through which ESRRG contributes to hearing remain largely unknown. Here, we report the results of comparative transcriptome profiling by RNA-Seq as part of our characterisation of the auditory phenotype in mice carrying a newly generated conditional knockout of Esrrg in the inner ear (Esrrgfl/fl;Sox10-Cre).

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Expression profiling by high throughput sequencing · Mus musculus
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Life Sciences
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RNA sequencing 65%
Provenance · 1 source records, 8 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE32956515 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[modality].local:modality:rna-seqenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (65%)
concepts[organism].NCBITaxon:10090source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title