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Omics · study · 2026

Transcriptomic profiling of irradiated HEK293T and NHLF cells to assess cell-type specific responses to γ-ray exposure

Listed in NCBI GEO

This RNA-seq dataset was generated to investigate the cell-type specificity of molecular responses to γ-ray exposure.

Description

We analyzed transcriptional profiles of irradiated HEK293T and NHLF cells to compare with brain microvascular endothelial cells and brain cells in a blood-brain barrier (BBB) microphysiological system (MPS). These data support our main study on radiation-induced BBB injury and reveal differential transcriptional responses across cell types.

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Expression profiling by high throughput sequencing · Homo sapiens
From keywords
Life Sciences
Inferred from text
RNA sequencing 65%
Provenance · 1 source records, 8 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE29457414 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[modality].local:modality:rna-seqenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (65%)
concepts[organism].NCBITaxon:9606source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title