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Imaging · study · 2026

Spatial chromatin architecture and accessibility co-profiling of mammalian tissues

Listed in NCBI GEO

Recent advancements of spatial omics techniques have enabled the profiling of different molecular features with spatial information.

Description

We developed Spatial-ATAC-Hi-C, which can provide spatially resolved, genome-wide joint-profiling of 3D genome organization and chromatin accessibility on tissue slides. Applying Spatial-ATAC-Hi-C in mouse and human brains, we revealed distinct chromatin architecture features and gene regulatory programs of different types of neuron and non-neuron cells in their original tissue locations.

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Stated by source
Mus musculus · Other
From keywords
Life Sciences
Provenance · 1 source records, 7 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE30762015 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:othersource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[organism].NCBITaxon:10090source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title