Omics · study · 2026
The stability of m6A-marked transcripts is linked to cell identity in planarians [Actinomycin D assay]
Listed in NCBI GEO
To test the effect of m6A on mRNA stability, we performed an Actinomycin D assay to monitor mRNA decay kinetics over time in wildtype, unc22 (RNAi) control, and mettl14 (RNAi) conditions.
Description
Resulting transcript abundance data were analyzed in a time-series analysis, which revealed two distinct gene clusters: genes that displayed significantly faster transcript decay upon mettl14 (RNAi), and genes exhibiting slower decay rates in mettl14 (RNAi) conditions.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE325nnn/GSE325805 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE325805 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1441991 ncbi.nlm.nih.gov/bioproject/PRJNA1441991 ↗
project · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing
- From keywords
- Life Sciences
Provenance · 1 source records, 6 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE325805 | 15 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |