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Data · dataset · 2026

<p>Binding of VA14_26 and V1WT_41 to WIV-1 RBD.</p>

Listed in UCL Research Data Repository

<p><b>A)</b> Close up view of K378 on WIV-1 RBD and its contact residue on VA14_26.

Description

Panel on the right depicts the coulomb density mesh around the residues at SD level 9, as implemented in ChimeraX_1.7.1. <b>B)</b> Close up view of R408 on WIV-1 RBD and its contact residues on VA14_26. Panel on the right depicts the coulomb density mesh around the residues at SD level 10.25, as implemented in ChimeraX_1.7.1. <b>C)</b> Comparison in neutralisation potency of VA14_26 Fab and IgG against SARS-CoV-2 (D614G), SARS-CoV-1 and WIV-1.

Mean values are plotted with error bars showing ± standard deviation (s.d.). <b>D)</b> Close up view of YYDRSG motif in V1WT_41 HCDR3 (green) in contact with WIV-1 RBD (grey), shown in cartoon representation. Regions outside the contact residues are turned transparent. Local structure with right-handed twist of beta hairpin is visible. <b>E)</b> Close up view of R408 on WIV-1 RBD and its contact residues on V1WT_41.

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Panel on the right depicts the coulomb density mesh around the residues at SD level 12.5, as implemented in ChimeraX_1.7.1. The data underlying this Figure can be found in <a href="plosbiology.org/article/info:doi/10.1371/journal.pbio.3003882#pbio.3003882.s010" target="_blank">S1 Data</a>.</p> <p>(TIF)</p>

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Provenance · 1 source records, 15 field assertions
SourceKeyLast seenRaw
UCL Research Data Repositoryoai:figshare.com:article/3404892111 d agoJSON v1
FieldAssertionExtractorEvidence
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concepts[field].anzsrc:group:3204mapping · rdr ucl ac ukvocabulary-mapper@1.0.0keywords['Immunology']
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