Excel · study · 2026
Transcriptomic profiling of cancer-associated fibroblasts (CAFs)/activated-hepatic stellate cells (HSCs) of murine cholangiocarcinoma (CCA) by NanoString GeoMX DSP.
Listed in NCBI GEO
Description
To study whether targeting Cd274/PD-L1 of HSCs by Cre/loxP approach in mice altered HSC transcriptome, HSC activation into CAFs, CCA/HSC interactions, and CCA growth, portal vein injection of SB mouse CCA cells (1 million cells per mouse) was performed on two months old Cd274+/+Col1A1Cre mice and two months old Cd274F/FCol1A1Cre mice. Murine CCA sections were prepared for transcriptomic profiling with the NanoString GeoMix DSP
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE296nnn/GSE296330 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE296330 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1258938 ncbi.nlm.nih.gov/bioproject/PRJNA1258938 ↗
project · from NCBI GEO
Topics
- Stated by source
- Mus musculus · Other
- From keywords
- Life Sciences
Provenance · 1 source records, 7 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE296330 | 15 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:other | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:10090 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |