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Omics · study · 2026

Deep invaginations of nuclear envelope coordinate spatial organization of chromatin

Listed in NCBI GEO

Epithelial maturation, increase in cellular packing density and associated suppression of MAPK signaling induces deep invaginations of the nuclear envelope (DINEs).

Description

The DINEs are associated with both transcriptionally active and repressed chromatin. Here, ATAC-seq was used to identify global chromatin accessibility in mature epitheliumcontaining DINEs in comparison a newly (2 h) seeded epithelium detached from mature epithelium (grown for 7 d) and not containing DINEs.

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Life Sciences
Provenance · 1 source records, 6 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE32626513 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:genome-binding-occupancy-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title