Factors influencing the evolution of pulmonary hypertension in previously healthy subjects recovering from a SARS-CoV-2 infection

(2)

Methods

We analyzed, by transthoracic echocardiography (TTE), the 3 and 6 months’ evolution of the estimated pulmonary artery pressures (sPAP) in 116 patients already diagnosed with PH or BPH due to COVID-19, during the first three subsequent waves of COVID-19. (3) Results: We documented a gradual, statistically significant reduction of SPAP values, but also an improvement of the parameters characterizing RVD after 3 and 6 months (p˂0.001).

This evolution was somewhat different between subjects infected with different viral strains and was related to the initial severity of the pulmonary injury and PH (adjusted R2=0.722, p˂0.001). (4) Conclusions: PH and RVD alleviate gradually during the recovery after COVID-19, but in some cases, they persist, suggesting the activation of pathophysiological mechanisms responsible for the self-propagation of PH. "Victor Babes" University of Medicine and Pharmacy, Timisoara.