Omics · study · 2026
Transcriptome Analysis of the Potential Mechanism of Juglans regia L. and Psoralea corylifolia Linn. Combination in Treating Osteoporosis Induced by Bilateral Ovariectomy in Rats
Listed in NCBI GEO
Postmenopausal osteoporosis is a prevalent clinical disorder in women.
Description
To elucidate the therapeutic mechanism underlying the combination of Juglans regia L. and Psoralea corylifolia Linn. for postmenopausal osteoporosis, we established bilateral ovariectomy-induced osteoporotic rat models and performed transcriptomic profiling. The results revealed that the anti-osteoporotic effects are predominantly mediated through ferroptosis-related pathways.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE293nnn/GSE293684 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE293684 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1245691 ncbi.nlm.nih.gov/bioproject/PRJNA1245691 ↗
project · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Rattus norvegicus
- From keywords
- Life Sciences
Provenance · 1 source records, 7 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE293684 | 14 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:10116 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |