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Table · dataset · 2023

Mosquito metabolism shapes life-history strategies of Plasmodium parasites

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This project simulates mosquito population dynamics and malaria transmission as described in the research paper "Mosquito metabolism shapes Plasmodium life-history traits".

Description

The modelling framework consists of an individual-based model with an extensive description of mosquito biology. Specifically, this is the first model that includes a description of nutrient allocation inside female mosquitoes and their interactions with growing malaria parasites.

Description of the data and file structure The data from our simulations is organized with variations based on different initial Tsp values and whether the model excluded (control) or included mosquito metabolism (metabolism). The directories are organized as follows: 1. Control simulations You will find three directories named "control_11", "control_12", and "control_13", where all results from the simulations excluding mosquito metabolism (control model), and with different starting conditions for Tsp, i.e., Tsp(0) = 11 - 13 days. 2.

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Metabolism simulations Similarly, you will find three directories named "metabolism_11", "metabolism_12", "metabolism_13", where results from simulations including the description of mosquito metabolism are stored. 3. Evolutionary simulations You will find four directories that follow a structure for both conditions (control and metabolism) and initial Tsp values (Tsp(0)) "condition_evo_TSP(0)". In every directory, you will find a subdirectory with all the simulated and analyzed data.

Every simulation produces the following files: femaleParameters.csv humanParameters.csv IncubationPeriod.csv larvaParameters.csv PopulationSize.csv TransmissionProfileMosquitoes.csv Code/Software The individual-based model was implemented in the C++ programming language. All analysis were performed using R version 3.5. The code is available under: gitlab.mpcdf.mpg.de/vectorbiology/mosquito_metabolism/vectorbornemodel_release

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Where it is published

Catalogue records · 1

Topics

Inferred from text
Life histories 75% · Simulation 75%
Provenance · 2 source records, 21 field assertions
SourceKeyLast seenRaw
Edmonddoi:10.17617/3.41DUIB13 d agoJSON v1
Edmonddoi:10.17617/3.41DUIB11 d agoJSON v1
FieldAssertionExtractorEvidence
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