Table · dataset · 2026
Video 1_Spinal granulocytic sarcoma with both extradural and intradural involvement: a case report.mp4
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Introduction<p>Granulocytic sarcoma (GS) is a rare extramedullary accumulation of myeloid blasts.
Description
Cases of GS with isolated intradural presentation sparing the underlying bone are extremely rare.</p>Case description<p>A 75-year-old male patient with a remote history of acute myeloid leukemia (AML) in 30-year remission presented with progressive lumbar radiculopathy. Magnetic Resonance Imaging (MRI) revealed intradural lesions spanning L2–S1, mimicking nerve sheath tumors.
The patient underwent emergency laminectomy and resection of a vascular, grayish-green L2 mass adherent to the cauda equina. Immunohistochemistry confirmed it was a GS (MPO+, CD43+, CD68+) with no evidence of bone marrow relapse. Following surgery and consolidation chemotherapy, the patient’s neurological status improved (ASIA C to D).
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However, he developed disseminated CNS relapse four months later and succumbed to disease progression 7 months postoperatively.</p>Conclusion<p>Isolated intradural GS constitutes a rare manifestation of extramedullary AML relapse and frequently masquerades radiologically as common benign nerve sheath tumors. While urgent surgical decompression facilitates significant neurological recovery, long-term survival is strictly dictated by the efficacy of systemic disease control.
Therefore, adopting a multidisciplinary strategy integrating intraoperative frozen-section analysis, rigorous immunohistochemical profiling, and early adjuvant chemotherapy is paramount for avoiding diagnostic delays and optimizing patient outcomes.</p>
Links
Where it is published
- DOI doi.org/10.3389/fonc.2026.1832811.s001 ↗
DOI / persistent id · from figshare com
Catalogue records · 1
- OAI-PMH record api.figshare.com/v2/oai?verb=GetRecord&metadataPrefix=oai_dc&identifier=oai%3Af… ↗
metadata API · from figshare com
Topics
- From keywords
- Astronomy & Astrophysics · Chemistry · Computer Science & AI · Earth & Environmental Science · Economics & Finance · Engineering · Humanities · Life Sciences · Medicine & Health · Ocean & Atmospheric Science · Social Science
- Inferred from text
- Disease 75% · Imaging 75% · Magnetic resonance imaging 75% · Video 75%
Provenance · 1 source records, 20 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| figshare | oai:figshare.com:article/33827764 | 12 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · figshare com | connector:figshare_com@1.0.0 | |
| concepts[disease].local:disease:disease | enrichment · figshare com | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[field].local:field:astronomy | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:chemistry | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:computer-science-ai | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:earth-environmental | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:economics-finance | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:engineering | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:humanities | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:medicine-health | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:ocean-atmospheric | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:social-science | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[modality].local:modality:imaging | enrichment · figshare com | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[modality].local:modality:mri | enrichment · figshare com | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[modality].local:modality:video | enrichment · figshare com | keyword-concept-rules@1.0.0 | title+description (75%) |
| description | source · figshare com | connector:figshare_com@1.0.0 | /metadata/dc/description |
| license | source · figshare com | connector:figshare_com@1.0.0 | /metadata/dc/rights |
| publication_date | source · figshare com | connector:figshare_com@1.0.0 | |
| title | source · figshare com | connector:figshare_com@1.0.0 | /metadata/dc/title |