Excel · study · 2026
Gene expression analysis in obsessive-compulsive disorder with and without comorbid neurodevelopmental disorders
Listed in NCBI GEO
Obsessive-compulsive disorder (OCD) is an intractable disease with a prevalence of 2-3%.
Description
Despite treatment with antidepressants, its pathogenesis remains unclear. Recent research suggests immunological mechanisms, particularly in OCD comorbid with neurodevelopmental disorders (NDD) like ASD, ADHD, and TD.
This study investigates immune factors involved in OCD and its comorbidities. To reveal the mechanism, RNA-Seq was performed.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE271nnn/GSE271268 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE271268 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1130831 ncbi.nlm.nih.gov/bioproject/PRJNA1130831 ↗
project · from NCBI GEO
- PubMed 40036942 pubmed.ncbi.nlm.nih.gov/40036942 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Homo sapiens
- From keywords
- Life Sciences
- Inferred from text
- Disease 75% · RNA sequencing 65%
Provenance · 1 source records, 9 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE271268 | 15 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[disease].local:disease:disease | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (65%) |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |