Omics · study · 2026
RNA-seq of paraventricular thalamus (PVT) and posterior insular cortex (pIC) in a mouse model of STZ-induced painful diabetic neuropathy with anxiety-like behavior
Listed in NCBI GEO
We generated poly(A)-selected, stranded mRNA-seq profiles from the paraventricular thalamus (PVT) and posterior insular cortex (pIC) of mice with streptozotocin (STZ; 200 mg/kg, i.p.)–induced painful diabetic neuropathy (PDN) and anxiety-like behavior, alongside vehicle controls.
Description
Twenty brain tissue samples (PVT and pIC from PDN and control groups) were sequenced. The dataset enables region-wise differential expression analysis and comparison of convergent versus region-specific remodeling between PVT and pIC.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE308nnn/GSE308534 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE308534 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1330606 ncbi.nlm.nih.gov/bioproject/PRJNA1330606 ↗
project · from NCBI GEO
- PubMed 42203788 pubmed.ncbi.nlm.nih.gov/42203788 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Mus musculus
- From keywords
- Life Sciences
- Inferred from text
- RNA sequencing 65%
Provenance · 1 source records, 8 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE308534 | 15 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (65%) |
| concepts[organism].NCBITaxon:10090 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |