Data for 14N1H HMQC solid-state NMR as a powerful tool to study amorphous formulations – an exemplary study of paclitaxel loaded polymer micelles

Poly(2-oxazoline) based polymer micelles loaded with different amounts of the cancer drug paclitaxel serve to highlight the possibilities offered by these experiments: While the very similar 15N chemical shifts hamper a solid-state NMR characterization based on this nucleus, 14N is a very versatile alternative. 14N-1H HMQC experiments yield well-separated signals, which are spread over a large ppm range, provide information on the symmetry of the nitrogen environment and probe 14N-1H through-space proximities.<br><br>Data record consists of a zip archive, organised into two subfolders containing NMR and PXRD data, and an explanatory readme file.

PXRD experiments folder contains raw data files as recorded under ambient conditions. NMR experiments folder contains raw data files as recorded for the compounds. If the record date is not stated within the experimental title, it is mentioned separately.