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Data · dataset · 2026

<p>Functional enrichment analysis links FABP5 to immune activation and NF-κB signaling pathways.</p>

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<p>(A) Heatmap of DEGs between high and low FABP5 expression groups.

Description

(B) Gene Ontology (GO) enrichment analysis of DEGs, showing significant biological processes (BP), cellular components (CC), and molecular functions (MF) related to immune regulation. (C) KEGG pathway enrichment analysis highlighting immune-related pathways associated with FABP5 expression, such as cytokine–cytokine receptor interaction, chemokine signaling, Th1/Th2 and Th17 cell differentiation, B cell receptor signaling, NF-κB signaling, PI3K–Akt signaling, T cell receptor signaling, IL-17 signaling, and JAK–STAT signaling.

(D) Correlation analysis revealed a positive association between FABP5 expression and cancer inflammatory gene signatures. (E) Heatmap showing co-upregulation of NF-κB pathway genes (NF-κB1, NF-κB2, RELA) in FABP5-high tumors.</p>

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Catalogue records · 1

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Provenance · 1 source records, 12 field assertions
SourceKeyLast seenRaw
ZivaHuboai:figshare.com:article/3402751511 d agoJSON v1
FieldAssertionExtractorEvidence
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concepts[field].anzsrc:group:3204mapping · zivahub uct ac zavocabulary-mapper@1.0.0keywords['Immunology']
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