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Omics · study · 2026

The impact of BSCI exposure on labour in pregnant mice after IL1A induction

Listed in NCBI GEO

To examine changes in chromatin accessibility involved in BSCI-mediated prevention of IL-1α-induced labour in pregnant mice, we conducted ATAC-seq on mouse myometrial tissues from four groups: Vehicle, IL-1α, BSCI and combined IL-1α with BSCI.

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Specifically, IL-1α is a method of labour induction, while administration of BSCI prior to and after administration of IL-1α prevents labour onset in mice. These data enable dissection of cis-regulatory elements involved in labour onset in response to IL-1α labour induction, as well as understanding of how these regions are modified in response to BSCI to prevent labour induction.

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Life Sciences
Provenance · 1 source records, 7 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE29230115 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:genome-binding-occupancy-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[organism].NCBITaxon:10090source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title