Omics · study · 2026
Targeting FKBP5 Preserves Mitochondrial Homeostasis through the CaMKKβ/AMPK Pathway to Attenuate Sepsis-Induced Acute Lung Injury
Listed in NCBI GEO
Description
Background
Sepsis-induced acute lung injury (ALI) remains a leading cause of mortality in critically ill patients, with endothelial barrier disruption and mitochondrial dysfunction serving as central pathological events. FK506-binding protein 5 (FKBP5) has been implicated in various inflammatory disorders, yet its specific role and underlying mechanism in septic ALI remain elusive.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE335nnn/GSE335386 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE335386 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1478452 ncbi.nlm.nih.gov/bioproject/PRJNA1478452 ↗
project · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Homo sapiens
- From keywords
- Life Sciences
Provenance · 1 source records, 7 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE335386 | 15 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |