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Omics · study · 2026

Bulk RNASeq of Stromal Subsets in Wildtype and GD T cell-deficent Mice in Biomaterial Implant Fibrosis

Listed in NCBI GEO

The main objective of this study is to investigate the role of gamma delta (GD) T cells on stromal cell behavior in chronic tissue injury and foreign body response (synthetic polycaprolactone PCL implant).

Description

We isolate key stromal cell populations (Fibroblasts and Endothelial Cells) from fibrotic PCL implants of wildtype (WT) and GD-deficient (GDKO) mice using FACS and compare their transcriptomic profile using bulk RNA-sequencing.

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Expression profiling by high throughput sequencing · Mus musculus
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Life Sciences
Inferred from text
RNA sequencing 65%
Provenance · 1 source records, 8 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE30614615 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[modality].local:modality:rna-seqenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (65%)
concepts[organism].NCBITaxon:10090source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title