Omics · study · 2026
Effect of overexpression of HMGA2 in human chondrosarcoma SW1353 cell line overexpression and control cells.
Listed in NCBI GEO
Chondrosarcoma (CHS) is a malignant bone tumour resistant to adjuvant treatment, with high-grade patients suffering an unfavorable prognosis.
Description
The high mobility group A2 (HMGA2) protein is a non‑histone architectural transcription factor influencing a variety of biological processes, including the cell cycle process, DNA damage repair process, apoptosis, senescence and epithelial‑mesenchymal transition. We here aimed to investigate the role of HMGA2 in CHS.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE289nnn/GSE289237 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE289237 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1221955 ncbi.nlm.nih.gov/bioproject/PRJNA1221955 ↗
project · from NCBI GEO
- PubMed 41964890 pubmed.ncbi.nlm.nih.gov/41964890 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Homo sapiens
- From keywords
- Life Sciences
- Inferred from text
- Cancer 65%
Provenance · 1 source records, 8 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE289237 | 13 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[disease].local:disease:cancer | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (65%) |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |