Effects of Environmental Tobacco Smoke exposure on brain functioning in never-smoking adolescents

This study therefore tested the associations between ETS exposure and ERPs reflecting cue-reactivity (P3, LPP), inhibitory control (N2, P3), and reward processing (anticipation P3 (P3), feedback-related negativity (FRN)) among never-smoking adolescents. Eighty-four never-smoking adolescents (Non-exposed = 32, Exposed = 52) were tested, while they performed a smoking cue-reactivity, a Go/NoGo, and a Monetary Incentive Delay (MID) task while ERPs were measured.

Exposed and non-exposed groups did not differ in ERPs reflecting smoking cue-reactivity, inhibitory control, and reward processing. A negative correlation between ETS exposure and the anticipatory P3 suggests reduced anticipatory reward sensitivity for non-drug rewards with increased levels of ETS exposure. However, since this effect was not consistent across analyses, no strong conclusions can be formulated.

In the current study, few participants reported high levels of ETS exposure; therefore, further study is necessary. Nevertheless, from this study, it can be concluded that low to moderate exposure to ETS during adolescence does not result in functional brain changes related to smoking cue-reactivity, inhibitory control, and reward processing. The codebook describes: 1) Recruitment, screening and inclusion, 2) Where data were collected, 3) Number of participants in the study and in addition contains a table which describes all the variables in the dataset.

The table also refers where in the syntax the code can be found. The syntax clearly describes how we made for example sumscores and subsequently what analyses we ran. A full description on the measures and how we created them is given in the Methodology file.