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Omics · study · 2026

RNAseq analysis of H69 cholangiocyte cell line stimulated with imidazole propionate

Listed in NCBI GEO

Primary sclerosing cholangitis (PSC) is a chronic inflammatory disease of the bile ducts associated with inflammatory bowel disease and an altered gut microbiota.

Description

Here we studied the transcriptomic impact of the gut microbial metabolite imidazole propionate and its precursor urocanate on a human cholangiocyte cell line.

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Stated by source
Expression profiling by high throughput sequencing · Homo sapiens
From keywords
Life Sciences
Inferred from text
Disease 75% · RNA sequencing 65%
Provenance · 1 source records, 9 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE34140915 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[disease].local:disease:diseaseenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (75%)
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[modality].local:modality:rna-seqenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (65%)
concepts[organism].NCBITaxon:9606source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title