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Omics · study · 2026

Single-cell RNA-seq of human non-lesional whole skin adjacent to an invasive melanoma excision scar, 5cm from the scar biopsy, and at a distant photoprotected site

Listed in NCBI GEO

Potentially carcinogenic mutations are widespread throughout the skin, and it is unknown why only some sites develop into a malignancy while most others continue to function normally.

Description

Using 10x Genomics Chomium Flex scRNA-seq, we explored differences in skin with similar levels of photodamage adjacent to and proximal to (5cm away from) a melanoma excision scar, and distant photoprotected skin.

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Expression profiling by high throughput sequencing · Homo sapiens
From keywords
Life Sciences
Inferred from text
RNA sequencing 65% · Single-cell RNA sequencing 65%
Provenance · 1 source records, 9 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE31889915 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[modality].local:modality:rna-seqenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (65%)
concepts[modality].local:modality:single-cell-rna-seqenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (65%)
concepts[organism].NCBITaxon:9606source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title