Imaging · study · 2026
Meningioma cell reprogramming and microenvironment interactions underlie brain invasion
Listed in NCBI GEO
Meningiomas brain invasion encumbers resection and increases the risk of tumor recurrence, but the molecular mechanisms underlying meningioma brain invasion are poorly understood.
Description
To identify molecular and cellular features of brain-invasive meningiomas, we performed spatial transcriptomic of brain-invasive meningiomas. Our results reveal that meningioma brain invasion is defined by molecular remodeling of tumor cells and functional interactions within the tumor microenvironment.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE299nnn/GSE299374 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE299374 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1271339 ncbi.nlm.nih.gov/bioproject/PRJNA1271339 ↗
project · from NCBI GEO
- PubMed 41476144 pubmed.ncbi.nlm.nih.gov/41476144 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Homo sapiens · Other
- From keywords
- Life Sciences
- Inferred from text
- Cancer 65%
Provenance · 1 source records, 8 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE299374 | 15 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[disease].local:disease:cancer | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (65%) |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:other | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |