Omics · study · 2026
Transcriptome analysis of NOMO-1 cells with MSLN knockout
Listed in NCBI GEO
MSLN is a newly identified AML target.
Description
Because MSLN is not expressed in normal bone marrow specimens, it is an attractive immunotherapy target. However, the function of MSLN in AML is unknown.
We generated NOMO-1 cells with CRISPR/CAS9 knockout and performed transcriptome analysis to understand the changes in gene expression profiles following loss of MSLN.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE306nnn/GSE306271 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE306271 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1310324 ncbi.nlm.nih.gov/bioproject/PRJNA1310324 ↗
project · from NCBI GEO
- PubMed 41866035 pubmed.ncbi.nlm.nih.gov/41866035 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Homo sapiens
- From keywords
- Life Sciences
Provenance · 1 source records, 7 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE306271 | 15 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |