Omics · study · 2026
Pleuromutilin Antibiotics Suppress Hepatocellular Carcinoma Growth
Listed in NCBI GEO
Pleuromutilin antibiotics(Lefamulin, Tiamulin, et al) has application potential in malignancies treatment.
Description
To mechanistically investigate the inhibitory activity against HCC of Lefamulin and Tiamulin, we treated Hepa1-6 cells with 37 μg/ml Lefamulin or Tiamulin for 2 days. Then the total RNA was performed RNA-Seq analysis.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE315nnn/GSE315390 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE315390 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1396644 ncbi.nlm.nih.gov/bioproject/PRJNA1396644 ↗
project · from NCBI GEO
- PubMed 41976277 pubmed.ncbi.nlm.nih.gov/41976277 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Mus musculus
- From keywords
- Life Sciences
- Inferred from text
- RNA sequencing 65%
Provenance · 1 source records, 8 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE315390 | 14 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (65%) |
| concepts[organism].NCBITaxon:10090 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |