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Data · dataset · 2025

In vitro evaluation of the concentration of fluoride released by pediatric toothpastes sold in the Dominican market

Listed in Teesside University Research Data Repository

Dental caries is among the most prevalent oral diseases in children, and its prevention is intimately associated with the utilization of fluoridated toothpastes.

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However, an inadequate concentration of fluoride, whether in excess or deficiency, can compromise the product's efficacy and safety as a preventative measure. The present study evaluated the fluoride concentration of three pediatric toothpastes available on the Dominican market (Colgate Smiles, Oral B Kids, and Oddent Flúor Infantil) in vitro, with the objective of verifying the compliance of these products with the manufacturer's claims and the limits established by health regulations.

A total of 75 samples (25 samples per brand) were subjected to analysis using the ion- selective electrode method, a technique that has been recognized for its accuracy in determining free fluoride concentrations. The procedure entailed the calibration of the instrument with standard solutions, the implementation of pH control utilizing TISAB III solution, and the execution of potentiometric measurement employing Mettler-Toledo equipment.

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The results obtained were expressed in ppm and subjected to statistical analysis. The findings indicated that Colgate Smiles contained a higher concentration of fluoride than indicated on its packaging, without compromising its preventive efficacy, while Oral B Kids had a slightly lower concentration but within acceptable ranges (500–1450 ppm). Conversely, Oddent Flúor Infantil exhibited levels that fell below the recommended minimum (377 ppm), a circumstance that has the potential to compromise its anticariogenic effectiveness.

These variations underscore discrepancies between the stated and the contained, and they highlight the necessity for enhanced regulation and quality control measures in children's dental products. It is concluded that, although some brands comply with the established parameters, others could represent a limitation in protection against caries. This information is of particular value to oral health professionals when formulating recommendations for safe and effective products.

Furthermore, it underscores the necessity of independent research to validate the actual content of products available on the local market.

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