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Omics · study · 2026

Transcriptomic effects of teriparatide on CAR cells from postmenopausal women

Listed in NCBI GEO

We employed 10X Genomics single cell RNA-sequencing to study the bone anabolic effects of teriparatide treatment on bone marrow Cxcl12-abundant reticular (CAR) cells from postmenopausal women.

Description

CAR cells, marked by the expression of the transcription factor Early B-cell Factor 3 (Ebf3), are a critical class of osteoblast progenitors participating in bone remodeling during adulthood. This study represents a single cell atlas of human bone marrow cells from postmenopausal women receving teriparatide for 3 months.

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Life Sciences
Provenance · 1 source records, 7 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE32623415 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[organism].NCBITaxon:9606source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title