Omics · study · 2026
RNA-binding protein NOC4L governs early natural killer cell development through dual post-transcriptional mechanisms
Listed in NCBI GEO
NOC4L is an RNA-binding protein required for early natural killer (NK) cell development.
Description
This submission contains: (1) RNA-seq of Noc4l conditional knockout and wild-type NK cells sorted from mouse spleen; (2) two batches of RIP-seq (anti-NOC4L antibody IP with no-antibody and input controls; FLAG-tagged NOC4L IP) identifying NOC4L-bound transcripts in NK cells. Conditional knockout was driven by Cd122-Cre (Il2rb-Cre), which targets the NK cell lineage.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE348nnn/GSE348067 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE348067 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1532762 ncbi.nlm.nih.gov/bioproject/PRJNA1532762 ↗
project · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Mus musculus · Other
- From keywords
- Life Sciences
- Inferred from text
- RNA sequencing 65%
Provenance · 1 source records, 9 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE348067 | 7 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[method].geo_series_type:other | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (65%) |
| concepts[organism].NCBITaxon:10090 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |