Omics · study · 2026
Bulk RNA-seq assessment of Kupffer cells isolated from control and infected A20fl/fl and Clec4f-Cre x A20fl/fl mice.
Listed in NCBI GEO
To understand how control KCs and activated KCs respond to systemic infection, we performed bulk RNA-sequencing of KCs isolated from the livers of naïve, LPS-treated (3.5mg/kg) or Salmonella typhimurium (S. Tm) infected A20fl/fl and Clec4f-Cre x A20fl/fl mice.
Description
LPS-treated mice and relevant controls were profiled 2hrs post LPS, while S. Tm infected mice and relevant controls were profiled 72hours post infection.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE342nnn/GSE342492 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE342492 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1508051 ncbi.nlm.nih.gov/bioproject/PRJNA1508051 ↗
project · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Mus musculus
- From keywords
- Life Sciences
- Inferred from text
- RNA sequencing 65%
Provenance · 1 source records, 8 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE342492 | 15 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (65%) |
| concepts[organism].NCBITaxon:10090 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |