Table · dataset · 2025
Effects of heavy particle irradiation and diet on object recognition memory in rats
Listed in NASA Data Portal
On long-duration missions to other planets astronauts will be exposed to types and doses of radiation that are not experienced in low earth orbit.
Description
Previous research using a ground-based model for exposure to cosmic rays has shown that exposure to heavy particles, such as 56Fe, disrupts spatial learning and memory measured using the Morris water maze. Maintaining rats on diets containing antioxidant phytochemicals for 2 weeks prior to irradiation ameliorated this deficit.
The present experiments were designed to determine: (1) the generality of the particle-induced disruption of memory by examining the effects of exposure to 56Fe particles on object recognition memory; and (2) whether maintaining rats on these antioxidant diets for 2 weeks prior to irradiation would also ameliorate any potential deficit. The results showed that exposure to low doses of 56Fe particles does disrupt recognition memory and that maintaining rats on antioxidant diets containing blueberry and strawberry extract for only 2 weeks was effective in ameliorating the disruptive effects of irradiation.
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The results are discussed in terms of the mechanisms by which exposure to these particles may produce effects on neurocognitive performance. This study derives behavior results from the novel object recognition assay. The original data derived from this study by Rabin et al. was transformed and used as part of a predictive modeling study by Dr.
Mora, Dr. Wyrobek, Dr. Ben Brown et al. The study files contain both the original data and the transformed data produced by both research teams.
For questions regarding the original study data and methods/assays, please contact the original study investigator and publication author Dr. Bernard Rabin (rabin@umbc.edu). For questions about the predictive modeling data files or how they were generated, please contact Dr.
Mora (animora@berkeley.edu).
Links
Get the data
- Resource purl.bioontology.org/ontology/NCBITAXON/10116 ↗
download · from data nasa gov
- Resource osdr.nasa.gov/bio/repo/data/studies/OSD-492 ↗
download · from data nasa gov
Where it is published
- NASA Data Portal dataset page data.nasa.gov/dataset/effects-of-heavy-particle-irradiation-and-diet-on-obje… ↗
landing page · from data nasa gov
- DOI doi.org/10.26030/vks4-1039 ↗
DOI / persistent id · from data nasa gov
Catalogue records · 1
- CKAN API data.nasa.gov/api/3/action/package_show?id=5129fd73-7b39-483c-b237-aafd3b72b… ↗
metadata API · from data nasa gov
Topics
- From keywords
- Astronomy & Astrophysics · Earth & Environmental Science · Life Sciences · Ocean & Atmospheric Science · Physics
- Inferred from text
- Space sciences 71%
Provenance · 1 source records, 12 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NASA Data Portal | 5129fd73-7b39-483c-b237-aafd3b72b698 | 12 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| concepts[field].anzsrc:group:5109 | enrichment · data nasa gov | taxonomy-embedding@1.0.0 | title+keywords+description (71%) |
| concepts[field].local:field:astronomy | mapping · data nasa gov | connector:data_nasa_gov@1.0.0 | |
| concepts[field].local:field:earth-environmental | mapping · data nasa gov | connector:data_nasa_gov@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · data nasa gov | connector:data_nasa_gov@1.0.0 | |
| concepts[field].local:field:ocean-atmospheric | mapping · data nasa gov | connector:data_nasa_gov@1.0.0 | |
| concepts[field].local:field:physics | mapping · data nasa gov | connector:data_nasa_gov@1.0.0 | |
| created_date | source · data nasa gov | connector:data_nasa_gov@1.0.0 | |
| description | source · data nasa gov | connector:data_nasa_gov@1.0.0 | /notes |
| license_text | source · data nasa gov | connector:data_nasa_gov@1.0.0 | |
| publication_date | source · data nasa gov | connector:data_nasa_gov@1.0.0 | |
| title | source · data nasa gov | connector:data_nasa_gov@1.0.0 | /title |
| updated_date | source · data nasa gov | connector:data_nasa_gov@1.0.0 |