Excel · study · 2026
Investigation of the Effect and Target of SchA in the Treatment of Triple-Negative Breast Cancer
Listed in NCBI GEO
SchA, one of the key bioactive components derived from Schisandra chinensis, was found in our study to exert a significant inhibitory effect on breast cancer cell viability.
Description
To elucidate the underlying mechanism, we integrated bioinformatics analysis with network pharmacology approaches to predict potential targets of SchA. The findings suggest that SchA may exert its anti-tumor effects by modulating IDO1 (indoleamine 2,3-dioxygenase 1), providing a foundation for further mechanistic investigation.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE328nnn/GSE328358 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE328358 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1454833 ncbi.nlm.nih.gov/bioproject/PRJNA1454833 ↗
project · from NCBI GEO
- PubMed 42220063 pubmed.ncbi.nlm.nih.gov/42220063 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Homo sapiens
- From keywords
- Life Sciences
- Inferred from text
- Cancer 75%
Provenance · 1 source records, 8 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE328358 | 15 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[disease].local:disease:cancer | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |