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Omics · study · 2026

SMARCA4 CUT&Tag profiling in parental and ARID1A-knockdown BxPC3 pancreatic cancer clones

Listed in NCBI GEO

This Series profiles SMARCA4 (BRG1) chromatin occupancy by CUT&Tag in parental BxPC3 pancreatic ductal adenocarcinoma cells and selected control or ARID1A-knockdown clonal populations.

Description

The data were generated to examine whether residual SMARCA4 preferentially occupies regulatory regions associated with increased and variable chromatin accessibility after ARID1A loss. Drosophila spike-in nuclei were included for quantitative normalization.

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Stated by source
Genome binding/occupancy profiling by high throughput sequencing · Homo sapiens
From keywords
Life Sciences
Inferred from text
Cancer 75%
Provenance · 1 source records, 8 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE34823815 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[disease].local:disease:cancerenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (75%)
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:genome-binding-occupancy-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[organism].NCBITaxon:9606source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title