Table · dataset · 2026
Data Sheet 1_ctDNA- and cfDNA-based liquid biopsy in bladder cancer and urothelial carcinoma: bibliometric mapping and cross-database coverage analysis, 2008-2025.zip
Listed in figshare
Background<p>Circulating tumour DNA (ctDNA), cell-free DNA (cfDNA) and urinary tumour DNA are increasingly studied in bladder cancer and urothelial carcinoma.
Description
We mapped the development, knowledge structure and clinical emphasis of this ctDNA/cfDNA-centred literature and assessed its coverage across three bibliographic databases.</p>Methods<p>Web of Science Core Collection (WoSCC), Scopus and PubMed/MEDLINE were searched on July 31, 2026, for records published in 2008-2025.
Reviewer-expanded strategies included liquid biopsy, ctDNA/cfDNA, molecular residual disease, molecular relapse, tumour-informed assays, urinary DNA, methylation, TERT and FGFR3. WoSCC was the primary mapping database; Scopus and PubMed/MEDLINE were coverage comparators. Python, VOSviewer and CiteSpace were used for descriptive and network analyses.
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Newly retrieved WoSCC records underwent duplicate independent screening and full third-reviewer quality control.</p>Results<p>The searches retrieved 1,903 WoSCC, 3,201 Scopus and 230 PubMed/MEDLINE records. After WoSCC deduplication and eligibility assessment, 494 records formed the main set and 698 formed a contextual set. The main set received 17,031 citations (median 19; interquartile range 7-42), and annual output reached 82 records in 2025.
Scopus covered 456/494 main records and PubMed/MEDLINE covered 93/494. Among 557 newly assessed records, the reviewers initially agreed on 433 (77.7%; Cohen’s kappa, 0.620); all records then underwent third-reviewer full-text quality control.</p>Conclusions<p>The expanded search identifies a larger DNA-focused literature than the original strategy and confirms unequal database coverage. Thematic clusters and citation bursts trace a shift from early methylation-marker research towards ctDNA-based molecular residual disease assessment and perioperative treatment stratification.
Bibliometric prominence describes research activity, not diagnostic accuracy, predictive validity or treatment benefit.</p>
Links
Where it is published
- DOI doi.org/10.3389/fonc.2026.1906152.s001 ↗
DOI / persistent id · from figshare com
Catalogue records · 1
- OAI-PMH record api.figshare.com/v2/oai?verb=GetRecord&metadataPrefix=oai_dc&identifier=oai%3Af… ↗
metadata API · from figshare com
Topics
- From keywords
- Astronomy & Astrophysics · Chemistry · Computer Science & AI · Earth & Environmental Science · Economics & Finance · Engineering · Humanities · Life Sciences · Medicine & Health · Ocean & Atmospheric Science · Social Science
- Inferred from text
- Cancer 75% · Disease 75% · Liquid biopsies 79%
Provenance · 1 source records, 19 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| figshare | oai:figshare.com:article/33717766 | 12 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · figshare com | connector:figshare_com@1.0.0 | |
| concepts[disease].local:disease:cancer | enrichment · figshare com | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[disease].local:disease:disease | enrichment · figshare com | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[field].anzsrc:field:321107 | enrichment · figshare com | taxonomy-embedding@1.0.0 | title+keywords+description (79%) |
| concepts[field].local:field:astronomy | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:chemistry | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:computer-science-ai | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:earth-environmental | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:economics-finance | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:engineering | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:humanities | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:medicine-health | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:ocean-atmospheric | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:social-science | mapping · figshare com | connector:figshare_com@1.0.0 | |
| description | source · figshare com | connector:figshare_com@1.0.0 | /metadata/dc/description |
| license | source · figshare com | connector:figshare_com@1.0.0 | /metadata/dc/rights |
| publication_date | source · figshare com | connector:figshare_com@1.0.0 | |
| title | source · figshare com | connector:figshare_com@1.0.0 | /metadata/dc/title |