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Omics · study · 2026

Identification of transcriptional changes in Human endothelial cell line after depletion of transcription factor Sox4 via siRNA.

Listed in NCBI GEO

To get a global perspective of SOX4 regulated genes, we performed RNA-seq in HUVECs.

Description

Using the cutoff criteria 1.3-fold change with 0.05 FDR, we identified 2500 genes, with roles in actin filament, circulatory system development, cell surface signaling, tube morphogenesis and lipid biosynthesis.

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From keywords
Life Sciences
Inferred from text
RNA sequencing 65%
Provenance · 1 source records, 9 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE32460912 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[method].geo_series_type:othersource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[modality].local:modality:rna-seqenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (65%)
concepts[organism].NCBITaxon:9606source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title