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Omics · study · 2026

Effect of TAPIR on mNSCs in self-renewing conditions

Listed in NCBI GEO

Cellular translation rates are hypothesized to impact various cellular processes.

Description

Changes in rRNA expression levels are often implicated in diseases. This study reports a novel approach using a CRISPR activation (referred to as TAPIR) to manipulate rRNA levels.

Induction of rRNA stimulates protein synthesis and cell proliferation, amongst others

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From keywords
Life Sciences
Provenance · 1 source records, 8 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE32458414 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[method].geo_series_type:othersource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[organism].NCBITaxon:10090source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title