Omics · study · 2026
Runx1 is a mediator of fibrotic activation and fibrotic memory in lung fibroblasts
Listed in NCBI GEO
Runx1 emerged as a transcription factor that was potentially regulating fibroblast activation and memory following intratracheal bleomycin injury.
Description
In order to examine this, fibroblasts were lineage traced and collected following bleomyicn induced fibrosis at the peak fibrotic time point, Day 14, and at the time of fibrotic recovery, Day 56. Runx1 ChIPseq was performed to assess Runx1 binding in regions of genes known to be associated with fibrosis.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE299nnn/GSE299276 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE299276 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1273736 ncbi.nlm.nih.gov/bioproject/PRJNA1273736 ↗
project · from NCBI GEO
- PubMed 41738205 pubmed.ncbi.nlm.nih.gov/41738205 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Genome binding/occupancy profiling by high throughput sequencing · Mus musculus
- From keywords
- Life Sciences
Provenance · 1 source records, 7 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE299276 | 14 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:genome-binding-occupancy-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:10090 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |