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Omics · study · 2026

Multidimensional Evaluation of UC-MSCs: Comparative Therapeutic Efficacy of Intrathecal and Intravenous Administration in a Rat Traumatic SCI Model

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Spinal cord injury (SCI) is a disabling neurological disorder with very limited therapeutic strategies.

Description

Human umbilical cord derived mesenchymal stem cells (UC MSCs) have shown therapeutic potential for SCI, but the optimal administration route remains undetermined. This study compared the efficacy and mechanisms of GMP grade UC MSCs delivered via intrathecal (MSC i.t) and intravenous (MSC i.v) injection in a rat traumatic SCI model.

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Life Sciences
Provenance · 1 source records, 7 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE34124615 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[organism].NCBITaxon:10116source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title