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Omics · study · 2026

Retinal waves are required for state-dependent visual processing

Listed in NCBI GEO

Spontaneous activity in the form of retinal waves propagates throughout the developing visual system during the first two weeks of life in the mouse.

Description

Here, we apply a range of approaches to the visual cortex of a unique mouse model, the Beta2fl/fl; Pax6α-Cre model, in which retinal waves are disrupted during the first week of life. We find that spontaneous activity during development is necessary for establishing neuronal transcription, synaptic connectivity, and function in the maturing brain.

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Life Sciences
Provenance · 1 source records, 7 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE21140615 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[organism].NCBITaxon:10090source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title