Data · dataset · 2023
Development of a novel, inexpensive and rapid multiplex allele-specific PCR assay for the detection of DPYD variants
Listed in REDU - Unicamp Institutional Research Data Repository
DPYD testing is recommended by drug agencies prior starting treatment with fluoropyrimidines to avoid severe adverse reactions.
Description
However, its implementation in poor regions of Brasil is complicated because of cost and the technologies used. Our aim was to develop a new and inexpensive DPYD assay including relevant variants in Latin American population that avoid the use of fluorescency equipment.
Specific oligonucleotides for a multiplex allele-specific PCR for 5 DPYD single nucleotide polymorphisms (SNPs) (c.1679T>G, c.1905+1G>A, c.2846A>T, c.1129.5923C>G and c.557A>G) were designed.
Links
Where it is published
- Dataverse dataset page redu.unicamp.br/dataset.xhtml?persistentId=doi%3A10.25824%2Fredu%2FZXTLB1 ↗
landing page · from redu unicamp br
- DOI doi.org/10.25824/redu/zxtlb1 ↗
DOI / persistent id · from redu unicamp br
Catalogue records · 1
- Dataverse API redu.unicamp.br/api/datasets/:persistentId/?persistentId=doi%3A10.25824%2Fredu… ↗
metadata API · from redu unicamp br
Topics
- Stated by source
- Medicine, Health and Life Sciences
- From keywords
- Cancer · Life Sciences · Medicine & Health
Provenance · 1 source records, 10 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| REDU - Unicamp Institutional Research Data Repository | doi:10.25824/redu/ZXTLB1 | 12 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| concepts[disease].local:disease:cancer | mapping · redu unicamp br | vocabulary-mapper@1.0.0 | keywords['Câncer'] |
| concepts[field].dataverse_subject:medicine-health-and-life-sciences | source · redu unicamp br | connector:redu_unicamp_br@1.0.0 | /subjects |
| concepts[field].local:field:life-sciences | mapping · redu unicamp br | connector:redu_unicamp_br@1.0.0 | /subjects |
| concepts[field].local:field:medicine-health | mapping · redu unicamp br | connector:redu_unicamp_br@1.0.0 | /subjects |
| created_date | source · redu unicamp br | connector:redu_unicamp_br@1.0.0 | |
| description | source · redu unicamp br | connector:redu_unicamp_br@1.0.0 | /description |
| publication_date | source · redu unicamp br | connector:redu_unicamp_br@1.0.0 | |
| title | source · redu unicamp br | connector:redu_unicamp_br@1.0.0 | /name |
| updated_date | source · redu unicamp br | connector:redu_unicamp_br@1.0.0 | |
| version_label | source · redu unicamp br | connector:redu_unicamp_br@1.0.0 |