← Search

Data · dataset · 2026

Comparative Proteomic Analysis of Heterozygous and Null DAT Knockout Rats

Listed in Teesside University Research Data Repository

Anastasia N. Vaganova, Zoya S. Fesenko, Sergey V. Shabelnikov, Alexey G. Mittenberg, Anna B. Volnova and Raul R. Gainetdinov.

Description

Comparative Proteomic Analysis of Heterozygous and Null DAT Knockout Rats. The present study revealed congruent results on rats with different doses of DAT gene knockout.

In both knockout groups, the basic carbohydrate and energetic metabolism seems to be deregulated in the striatum compared to the WT littermates. These results are in common trend with current literature data. Expectedly, the deregulation pattern is more pronounced in homozygous DAT-KO rats than in DAT-Het.

Read the rest (1 more)

Manuscript submitted to the International Journal of Molecular Sciences. The raw mass spec data (DAT_rats_decoy) and *.mzid/Scaffold v.4.0 files (DAT_rats)

Links

Where it is published

Catalogue records · 1

Topics

Inferred from text
Proteomics and metabolomics 76%
Provenance · 1 source records, 12 field assertions
SourceKeyLast seenRaw
Teesside University Research Data Repositoryoai:data.mendeley.com/6tsdm23n2y.111 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · researchdata tees ac ukconnector:researchdata_tees_ac_uk@1.0.0
concepts[field].anzsrc:field:310205enrichment · researchdata tees ac uktaxonomy-embedding@1.0.0title+keywords+description (76%)
concepts[field].local:field:earth-environmentalmapping · researchdata tees ac ukconnector:researchdata_tees_ac_uk@1.0.0
concepts[field].local:field:engineeringmapping · researchdata tees ac ukconnector:researchdata_tees_ac_uk@1.0.0
concepts[field].local:field:humanitiesmapping · researchdata tees ac ukconnector:researchdata_tees_ac_uk@1.0.0
concepts[field].local:field:life-sciencesmapping · researchdata tees ac ukconnector:researchdata_tees_ac_uk@1.0.0
concepts[field].local:field:social-sciencemapping · researchdata tees ac ukconnector:researchdata_tees_ac_uk@1.0.0
concepts[modality].local:modality:mass-spectrometrymapping · researchdata tees ac ukvocabulary-mapper@1.0.0keywords['Mass Spectrometry']
descriptionsource · researchdata tees ac ukconnector:researchdata_tees_ac_uk@1.0.0/metadata/dc/description
licensesource · researchdata tees ac ukconnector:researchdata_tees_ac_uk@1.0.0/metadata/dc/rights
publication_datesource · researchdata tees ac ukconnector:researchdata_tees_ac_uk@1.0.0
titlesource · researchdata tees ac ukconnector:researchdata_tees_ac_uk@1.0.0/metadata/dc/title