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}NCL Data2026 · Sequencing
Data Sheet 1_Comparison of three routine methods for the identification of Kerstersia gyiorum from routine diagnostics and review of the literature.pdfIntroduction<p>Since its first description in 2003, clinical case reports have repeatedly documented that the bacterial species Kerstersia gyiorum is a human pathogen. K. gyiorum has been described in the context of wound and middle ear infections, has been found in urine samples, and has even been recognized as a causative agent of septicemia. However, the pathogenic potential of K. gyiorum canno
NCL Data2026 · Sequencing
DataSheet1_Diversity of eukaryote plankton and phycotoxins along the West Kalaallit Nunaat (Greenland) coast.zip<p>The West Kallaallit Nunaat (Greenland) coast, characterized by a variety of fjords, bays, and channels influenced by glacier melting and Atlantic and Arctic waters, is one of the most affected ecosystems by climate change. Here, we combine oceanography, optics, microscopy, high throughput sequencing, microalgal strain establishments, and state-of-the-art analytical methods to fully characterize
NCL Data2026 · Sequencing
Table1_Diversity of eukaryote plankton and phycotoxins along the West Kalaallit Nunaat (Greenland) coast.xlsx<p>The West Kallaallit Nunaat (Greenland) coast, characterized by a variety of fjords, bays, and channels influenced by glacier melting and Atlantic and Arctic waters, is one of the most affected ecosystems by climate change. Here, we combine oceanography, optics, microscopy, high throughput sequencing, microalgal strain establishments, and state-of-the-art analytical methods to fully characterize
NCL Data2026 · Genome sequencing
<p>Delamanid (DLM) and pretomanid (Pa) minimum inhibitory concentrations (MICs), genomic variants, lineage, and clinical characteristics of 17 <i>Mycobacterium tuberculosis</i> isolates included in the study.</p><p>Delamanid (DLM) and pretomanid (Pa) minimum inhibitory concentrations (MICs), genomic variants, lineage, and clinical characteristics of 17 <i>Mycobacterium tuberculosis</i> isolates included in the study.</p>
figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Single-cell RNA sequencing
Data Sheet 1_Exploiting RAG1-deficient chickens to construct a single-cell transcriptional atlas of chicken heterophils during inflammation.xlsxIntroduction<p>Avian heterophils naturally lack myeloperoxidase (MPO), making chicken a unique evolutionary model for investigating MPO-independent innate immune strategies. However, the molecular programs governing heterophil maturation and activation remain largely unexplored.</p>Methods<p>Using single-cell RNA sequencing in a RAG1-deficient chicken model, we mapped heterophil maturation during
figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Single-cell RNA sequencing
Supplementary file 1_Case Report: Melanocyte-associated mTORC1-related molecular features in an atypical large congenital melanocytic naevus.docx<p>Congenital melanocytic naevi (CMN) are usually associated with activating alterations in NRAS or BRAF, but some extensive lesions lack detectable canonical hotspot variants. We report a 9-year-old boy with a large craniofacial CMN involving the face, scalp, upper eyelid and bulbar conjunctiva, with deep extension, mechanical ptosis and secondary amblyopia. Histology showed benign dermal melanoc
figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Single-cell RNA sequencing
Table 2_Longitudinal single-cell analysis identifies a chemotherapy-suppressed proliferative program associated with adverse prognosis in neuroblastoma.xlsxBackground<p>High-risk neuroblastoma frequently relapses after intensive therapy, but the treatment-associated malignant-neuroblast programs that inform baseline tumor risk remain incompletely defined. We used longitudinal single-cell/single-nucleus RNA-seq data to identify post-treatment transcriptional changes in malignant neuroblasts and evaluated their prognostic relevance in diagnostic bulk R
figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Single-cell RNA sequencing
Table 1_Exploiting RAG1-deficient chickens to construct a single-cell transcriptional atlas of chicken heterophils during inflammation.docxIntroduction<p>Avian heterophils naturally lack myeloperoxidase (MPO), making chicken a unique evolutionary model for investigating MPO-independent innate immune strategies. However, the molecular programs governing heterophil maturation and activation remain largely unexplored.</p>Methods<p>Using single-cell RNA sequencing in a RAG1-deficient chicken model, we mapped heterophil maturation during
Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Genome sequencing
MRSP WGS-AST boundary benchmark: reproducibility package (revision version)MRSP WGS-AST boundary benchmark: reproducibility package (revision version). Reproducibility package for the Microbial Genomics manuscript MGEN-D-26-00487 (de Souza and Santoro): Staphylococcus pseudintermedius whole-genome sequencing antimicrobial susceptibility boundary benchmark with a training-only-dictionary pangenome projection, restricted-shell model inputs, frozen prediction chains and out
figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Single-cell RNA sequencing
Data Sheet 3_Exploiting RAG1-deficient chickens to construct a single-cell transcriptional atlas of chicken heterophils during inflammation.xlsxIntroduction<p>Avian heterophils naturally lack myeloperoxidase (MPO), making chicken a unique evolutionary model for investigating MPO-independent innate immune strategies. However, the molecular programs governing heterophil maturation and activation remain largely unexplored.</p>Methods<p>Using single-cell RNA sequencing in a RAG1-deficient chicken model, we mapped heterophil maturation during
figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Single-cell RNA sequencing
Table 1_Longitudinal single-cell analysis identifies a chemotherapy-suppressed proliferative program associated with adverse prognosis in neuroblastoma.xlsxBackground<p>High-risk neuroblastoma frequently relapses after intensive therapy, but the treatment-associated malignant-neuroblast programs that inform baseline tumor risk remain incompletely defined. We used longitudinal single-cell/single-nucleus RNA-seq data to identify post-treatment transcriptional changes in malignant neuroblasts and evaluated their prognostic relevance in diagnostic bulk R
figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Single-cell RNA sequencing
Single-cell RNA-seq data from Sakimoto et al, 2024<p dir="ltr">Seurat object (Filtered, processed scRNA-seq data) from Sakimoto et al, BJC Reports, 2024 (https://doi.org/10.1038/s44276-024-00112-3).</p>
figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Single-cell RNA sequencing
Data Sheet 4_Exploiting RAG1-deficient chickens to construct a single-cell transcriptional atlas of chicken heterophils during inflammation.xlsxIntroduction<p>Avian heterophils naturally lack myeloperoxidase (MPO), making chicken a unique evolutionary model for investigating MPO-independent innate immune strategies. However, the molecular programs governing heterophil maturation and activation remain largely unexplored.</p>Methods<p>Using single-cell RNA sequencing in a RAG1-deficient chicken model, we mapped heterophil maturation during
figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Single-cell RNA sequencing
Data Sheet 2_Exploiting RAG1-deficient chickens to construct a single-cell transcriptional atlas of chicken heterophils during inflammation.xlsxIntroduction<p>Avian heterophils naturally lack myeloperoxidase (MPO), making chicken a unique evolutionary model for investigating MPO-independent innate immune strategies. However, the molecular programs governing heterophil maturation and activation remain largely unexplored.</p>Methods<p>Using single-cell RNA sequencing in a RAG1-deficient chicken model, we mapped heterophil maturation during
figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Genome sequencing
Data Sheet 1_Comparative genomic analysis of Staphylococcus spp. and Mammaliicoccus sciuri suggests potential sharing between dogs and their owners.pdfIntroduction<p>Staphylococci are a diverse group of bacteria commonly found on the skin and mucosal surfaces of humans and animals. Members of the genus can transition from commensalism to opportunistic pathogenicity. The extent to which close contact facilitates transmission of staphylococci remains misunderstood, particularly at the genomic level. In this context, the present study aimed to inve
Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Sequencing
Differentially expressed LncRNAs in the lung tissue of BPD mice<p dir="ltr"><b>Data source and experimental design</b></p><p dir="ltr">This dataset contains transcriptomic data from lung tissues of a neonatal mouse model of bronchopulmonary dysplasia (BPD). BPD was induced in newborn C57BL/6 mice by intranasal administration of lipopolysaccharide (LPS; 3 μg/10 μL) on postnatal days 3, 5, 7, and 10. Control mice received an equal volume of saline. Lung tissues
figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Single-cell RNA sequencing
Table 3_Longitudinal single-cell analysis identifies a chemotherapy-suppressed proliferative program associated with adverse prognosis in neuroblastoma.xlsxBackground<p>High-risk neuroblastoma frequently relapses after intensive therapy, but the treatment-associated malignant-neuroblast programs that inform baseline tumor risk remain incompletely defined. We used longitudinal single-cell/single-nucleus RNA-seq data to identify post-treatment transcriptional changes in malignant neuroblasts and evaluated their prognostic relevance in diagnostic bulk R
ZivaHub + Deakin Research Online + DMU Figshare2026 · Sequencing
Pathogenomic analysis and molecular diagnosis of microbial keratitisIntroduction: Microbial keratitis (MK) is a serious infection of the cornea and a leading cause of monocular blindness globally. Incidence rates of MK are increasing due to a rise in associated risk factors such as contact lens use. To guide selection of the most appropriate antimicrobial therapy and ensure the best possible visual outcome for the patient, it is critical for ophthalmologists to ra
ZivaHub + Deakin Research Online + DMU Figshare + HKU DataHub + Swinburne Figshare + DaYta Ya Rona + SUNScholarData + figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Single-cell RNA sequencing
Table 1_Single-cell profiling of peripheral immune remodeling in BK polyomavirus–associated nephropathy after kidney transplantation.xlsx<p>BK polyomavirus–associated nephropathy (BKPyVAN) remains a major cause of allograft dysfunction after kidney transplantation. To define peripheral immune signatures associated with distinct clinical states of BKPyV infection, we performed single-cell RNA sequencing of peripheral blood mononuclear cells from kidney transplant recipients across three clinical states: stable graft function (n = 1)
ZivaHub + Deakin Research Online + DMU Figshare + HKU DataHub + Swinburne Figshare + DaYta Ya Rona + SUNScholarData + figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Single-cell RNA sequencing
Table 4_Single-cell profiling of peripheral immune remodeling in BK polyomavirus–associated nephropathy after kidney transplantation.xlsx<p>BK polyomavirus–associated nephropathy (BKPyVAN) remains a major cause of allograft dysfunction after kidney transplantation. To define peripheral immune signatures associated with distinct clinical states of BKPyV infection, we performed single-cell RNA sequencing of peripheral blood mononuclear cells from kidney transplant recipients across three clinical states: stable graft function (n = 1)
ZivaHub + Deakin Research Online + DMU Figshare2026 · Sequencing
From taxa to transcripts: investigating the snail holobiont in the context of helminth infectionHelminth parasites have complex life cycles that often require intermediate invertebrate hosts, such as freshwater snails. While much is known about the immunology and pathology of helminth infections, the role of the host-associated microbiome in these interactions remains underexplored. This thesis investigates the dynamic interplay between schistosome parasites, their snail hosts, and the host
HKU DataHub + Swinburne Figshare + DaYta Ya Rona + SUNScholarData + figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · RNA sequencing
All_genes_pseudobulk_Healthy_4wk_6wk<p dir="ltr">Pseudobulk genome-wide transcription from whole adult mouse lung. Three groups: healthy (no treatment), 4wkHDM (after 4 weeks of intranasal house dust mite exposure), and 6wkHDM (after 6 weeks of intranasal house dust mite exposure).</p>
ZivaHub + Deakin Research Online + DMU Figshare2026 · Single-cell RNA sequencing
Image 4_MTHFD1L-associated branched-chain amino acid degradation transcriptional signature represents a conserved metabolic program in Epstein-Barr virus-associated malignancies.jpg<p>Epstein-Barr virus (EBV)-associated malignancies encompass multiple tumor types with distinct tissue origins, yet the extent to which they share conserved metabolic programs remains poorly understood. Here, we performed an integrated cross-cancer transcriptomic analysis of nasopharyngeal carcinoma, EBV-associated gastric cancer, and EBV-associated plasmablastic lymphoma to identify conserved me
ZivaHub + Deakin Research Online + DMU Figshare2026 · Genome sequencing
A study of the bacterial ecology of a chocolate ingredient production environment and characterisation of Salmonella species a zoonotic food-borne bacteria of importance to this food industryThe safe production of chocolate is a critical issue to both the consumer and the brand, requiring the application of Hazard Analysis Critical Control Points (HACCP) system across the production process. These production environments are challenged on occasion with different hazards of importance to food safety. Control of bacterial hazards as exemplified by pathogenic bacteria like Salmonella is
ZivaHub + Deakin Research Online + DMU Figshare + HKU DataHub + Swinburne Figshare + DaYta Ya Rona + SUNScholarData + figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · RNA sequencing
Supplementary data for transcriptomic analysis of suicide in bipolar disorder<p dir="ltr">This repository contains supplementary datasets associated with the manuscript, including differential gene expression (DEG) results, Gene Ontology biological process (GO BP) enrichment analyses, gene lists for WGCNA modules, and functional annotations of co-expression modules.</p>