NCL Data2026 · dataset
Data Sheet 1_IgG N-glycosylation in autoimmune diseases.pdf<p>IgG is the most abundant antibody in the human circulation. It carries a single conserved glycosylation site, Asparagine 297, in its Fc domain. This N-glycan is critical for the ability of the antibody to activate immune cells via binding to, and cross-linking Fc receptors in order to elicit functional responses. First documented in the context of rheumatoid arthritis (RA), the IgG N-glycan may
NCL Data2026 · dataset
pone.0356818.t001 - <p> </p><div><p><i>Leishmania</i> CK1.2 (L-CK1.2) is a serine/threonine protein kinase essential for the survival of the protozoan parasite <i>Leishmania</i>, the causative agent of leishmaniasis. This study investigates the dynamic localization pattern of L-CK1.2 and the broad spectrum of its interacting partners within the parasite. Using proteomic analysis and confocal microscopy, we identified 230 L-C
NCL Data2026 · Crystal structure
Edge-Dependent Capacitive Response and Geometry-Tunable Metallization Field in Same-Lattice Graphene/Graphane/Graphene Nanoribbon NanocapacitorsUsing first-principles density functional theory calculations, this study investigates how crystallographic edge geometry and independently varied graphene-segment and graphane-spacer widths govern the field-induced response of same-lattice graphene/graphane/graphene nanoribbon nanocapacitors. Patterned hydrogenation creates laterally integrated, electronically distinct regions within a common car
NCL Data2026 · dataset
Inpatient Dataset of Guillain-Barré Syndrome Patients in Western China (2020–2026)<p dir="ltr">This data descriptor encompasses medical records from 1,419 inpatients diagnosed with Guillain-Barré Syndrome (GBS). The data were collected from six provincial-level tertiary general hospitals across Chongqing, Ningxia, Kunming, and Guizhou. The records span a collection period from January 2020 to September 2026.</p><p><br></p><p dir="ltr">For each patient, the medical records inclu
NCL Data2026 · dataset
<p>Baseline characteristics of healthy dogs, dogs with hypothyroidism and NTIS.</p><p>Baseline characteristics of healthy dogs, dogs with hypothyroidism and NTIS.</p>
NCL Data2026 · dataset
<p>Baseline and laboratory characteristics.</p><div> <p>Background</p><p>Diagnosing canine hypothyroidism remains challenging because decreased total thyroxine (tT4) concentrations are not specific for hypothyroidism and are frequently observed in dogs with non-thyroidal illness syndrome (NTIS). Although additional thyrotropin (TSH) and free thyroxine (fT4) measurements may improve diagnostic accuracy, differentiation between hypothyroidism an
NCL Data2026 · dataset
<p>Wasserstein distance for varying leakage percentages across datasets.</p><p>Wasserstein distance for varying leakage percentages across datasets.</p>
NCL Data2026 · dataset
<p>Demographics of the participants.</p><div> <p>Background</p><p><i>Mycoplasma pneumoniae</i> accounts for a significant proportion of pathogens responsible for community-acquired pneumonia (CAP). Identifying <i>Mycoplasma pneumoniae</i> pneumonia (MPP) is challenging but essential for guiding early and appropriate antibiotic use.</p> <p>Methods</p><p>We developed a predictive model using data from hospitalized CAP patients diagnosed w
NCL Data2026 · dataset
<p>Supplementary data tables.</p><p>This Excel file includes the primer sequences used for quantitative real-time PCR (qPCR) validation of the five hub target genes.</p> <p>(XLSX)</p>
NCL Data2026 · dataset
Data Sheet 2_IgG N-glycosylation in autoimmune diseases.docx<p>IgG is the most abundant antibody in the human circulation. It carries a single conserved glycosylation site, Asparagine 297, in its Fc domain. This N-glycan is critical for the ability of the antibody to activate immune cells via binding to, and cross-linking Fc receptors in order to elicit functional responses. First documented in the context of rheumatoid arthritis (RA), the IgG N-glycan may
NCL Data2026 · dataset
<p>Performance of the single- and five-marker models.</p><p>Performance of the single- and five-marker models.</p>
NCL Data2026 · dataset
<p>Anthropometrics and clinical characteristics of study participant.</p><p>Anthropometrics and clinical characteristics of study participant.</p>
NCL Data2026 · dataset
<p>Pairwise comparisons of body weight between healthy dogs, dogs with hypothyroidism, and dogs with nonthyroidal illness syndrome (NTIS).</p><p>Pairwise comparisons of body weight between healthy dogs, dogs with hypothyroidism, and dogs with nonthyroidal illness syndrome (NTIS).</p>
NCL Data2026 · dataset
<p>The molecular docking results of the five key genes with the BPA.</p><p>The molecular docking results of the five key genes with the BPA.</p>
NCL Data2026 · dataset
<p>Classification of hypothyroid and NTIS dogs based on rT3 and fT4d reference intervals.</p><p>Classification of hypothyroid and NTIS dogs based on rT3 and fT4d reference intervals.</p>
NCL Data2026 · dataset
<p>Demographics, clinical grades and outcomes of the study participants.</p><p>Demographics, clinical grades and outcomes of the study participants.</p>
NCL Data2026 · dataset
<p>Laboratory parameters comparison between groups.</p><div> <p>Background</p><p><i>Mycoplasma pneumoniae</i> accounts for a significant proportion of pathogens responsible for community-acquired pneumonia (CAP). Identifying <i>Mycoplasma pneumoniae</i> pneumonia (MPP) is challenging but essential for guiding early and appropriate antibiotic use.</p> <p>Methods</p><p>We developed a predictive model using data from hospitalized CAP patients diagnosed w
NCL Data2026 · dataset
<p>Diagnostic performance of different rT3 cut-off values for differentiating hypothyroidism from NTIS.</p><p>Diagnostic performance of different rT3 cut-off values for differentiating hypothyroidism from NTIS.</p>
NCL Data2026 · dataset
<p>Adherence in the respondents’ ED to the 12 workforce recommendations and association with burnout. Numbers are n (%). Chi-square tests.</p><p>Adherence in the respondents’ ED to the 12 workforce recommendations and association with burnout. Numbers are n (%). Chi-square tests.</p>
NCL Data2026 · dataset
<p>Primers used for qPCR.</p><div><p>Pseudorabies virus (PRV), an alphaherpesvirus, establishes lifelong latency in neurons and requires efficient reactivation for pathogenesis. Thymidine kinase (TK), encoded by UL23, is a key virulence factor essential for viral replication in non-dividing cells and for reactivation from latency; however, the regulatory mechanisms governing TK function remain poorly defined. Here, we identif
NCL Data2026 · dataset
<p>Supplementary data tables.</p><p>This Excel file includes the following data sheets: Molecular docking binding energies of BPA against all 29 overlapping targets.</p> <p>(XLSX)</p>
NCL Data2026 · dataset
<p>Sociodemographic characteristics of study participants.</p><p>Sociodemographic characteristics of study participants.</p>
NCL Data2026 · dataset
<p>Summary of the datasets utilized here.</p><div><p>A central challenge in downstream single-cell RNA sequencing (scRNA-seq) analysis is the high-dimensional, small-sample (HDSS) regime, often compounded by class imbalance from rare cell types. These factors hinder robust feature (gene) selection and cell clustering and limit the realism of samples generated by existing simulators. We introduce <i>GARAGE</i>, a <b>G</b>raph-<b>A</b>ttentive
NCL Data2026 · dataset
<p>Aversion protocol.</p><div><p>Animals perceive their immediate environment through their sensory systems. While these systems rely on well-defined neuronal circuits and receptor proteins encoded by the genome, they can also be modulated by internal physiological conditions or exogenous factors. We have previously shown that the presence of certain pathogenic bacteria in the larval gut can alter the specificity of bacte
NCL Data2026 · dataset
<p>List of potential L-CKAP<i>host</i> in murine BMDM macrophages.</p><p>Sheet all data: List of all quantified proteins in promastigotes and axenic amastigotes. CK1.2 binding partners: Selected proteins followed the following criteria: proteins identified with 2 or more distinct peptides, a fold change ratio CK1.2-V5/mock above 2 and a p-value below 0.05 in at least two replicates.</p> <p>(XLSX)</p>