Omics · study · 2026
Transcriptomic profiling of human RPTECs following TNFα and IFNγ stimulation at early and late time points
Listed in NCBI GEO
Renal proximal tubule epithelial cells (RPTECs) were stimulated with TNFα, IFNγ, or a combination of TNFα and IFNγ to characterize cytokine-induced transcriptional responses.
Description
Bulk RNA sequencing was performed at 3 h and 12 h following treatment to capture early and sustained gene expression changes. This dataset enables analysis of inflammatory signaling dynamics and cytokine-specific versus cooperative transcriptional programs in human tubular epithelial cells
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE319nnn/GSE319877 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE319877 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1335268 ncbi.nlm.nih.gov/bioproject/PRJNA1335268 ↗
project · from NCBI GEO
- PubMed 42497247 pubmed.ncbi.nlm.nih.gov/42497247 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Homo sapiens
- From keywords
- Life Sciences
- Inferred from text
- RNA sequencing 75% · Sequencing 75%
Provenance · 1 source records, 9 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE319877 | 15 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[modality].local:modality:sequencing | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[organism].NCBITaxon:9606 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |